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| Management number | 204590464 | Release Date | 2025/10/14 | List Price | $22.34 | Model Number | 204590464 | ||
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Simparica Trio Chews for Dogs 5.6-11.0 lbs are once-monthly, broad-spectrum chewable tablets formulated to protect small breed dogs from fleas, ticks, heartworms, roundworms, and hookworms. Developed by Zoetis, this FDA-approved, veterinarian-recommended medication offers a fast-acting and long-lasting defense against both external and internal parasites.
This liver-flavored chew provides 30 days of continuous parasite prevention, eliminating the need for messy topical treatments or multiple medications. Designed specifically for toy and small dogs weighing between 5.6-11.0 lbs, Simparica Trio ensures year-round protection in a single, easy-to-administer chew.
Simparica Trio is available in different dosage strengths to ensure optimal protection for dogs of all sizes. Find the perfect dose for your furry friend:
✅ Simparica Trio Chewable Tablets for Puppies 2.8-5.5 lbs
✅ Simparica Trio Chewable Tablets for Dogs 11.1-22.0 lbs
✅ Simparica Trio Chewable Tablets for Dogs 22.1-44.0 lbs
✅ Simparica Trio Chewable Tablets for Dogs 44.1-88.0 lbs
✅ Simparica Trio Chewable Tablets for Dogs 88.1-132.0 lbs
Ensure your dog gets the right dosage for their size and weight to receive full-spectrum parasite protection. 🐶💙
✔ Triple-Action Parasite Protection – Prevents heartworm disease, eliminates fleas and ticks, and treats intestinal worms.
✔ Fast-Acting & Long-Lasting – Starts killing fleas within 4 hours and ticks within 8 hours, offering month-long protection.
✔ Vet-Approved & FDA-Certified – Safe for small dogs as young as 8 weeks old, with a proven high safety margin.
✔ Highly Palatable Chew – No more struggling with tablets or messy spot-on treatments—delicious liver flavor makes dosing easy.
✔ Scientifically Proven Efficacy – Effectively eliminates 5 species of ticks, fleas, and gastrointestinal parasites.
| Parasite | Effectiveness |
|---|---|
| Fleas (Ctenocephalides felis) | 100% within 8 hours |
| Ticks (5 species) | 98.9% |
| Roundworms (Toxocara canis, Toxascaris leonina) | 99.2% |
| Hookworms (Ancylostoma caninum, Uncinaria stenocephala) | 94% |
Simparica Trio chews contain three active ingredients that work together to provide comprehensive parasite control:
By combining ectoparasiticidal (external parasite control) and endoparasiticidal (internal parasite control) properties, Simparica Trio offers full-body protection for small breed dogs.
| Dog Weight (lbs) | Sarolaner (mg) | Moxidectin (mg) | Pyrantel (mg) | Tablets Per Month |
|---|---|---|---|---|
| 5.6 – 11.0 lbs | 6 mg | 0.12 mg | 25 mg | 1 tablet |
Eliminates 5 common tick species, including:
For broader parasite protection, some pet owners opt for Simparica Trio, which protects against:
| Feature | Simparica | Simparica Trio |
|---|---|---|
| Kills Fleas & Ticks | ✅ Yes | ✅ Yes |
| Prevents Heartworm Disease | ❌ No | ✅ Yes |
| Treats Intestinal Worms (Roundworms & Hookworms) | ❌ No | ✅ Yes |
| Dosing Schedule | Monthly | Monthly |
If your dog also needs heartworm prevention, consider upgrading to Simparica Trio heartworm and flea prevention for complete parasite control.
Simparica Trio is safe for dogs 8 weeks and older weighing at least 2.8 lbs. However, some dogs may experience mild side effects.
⚠ Use with caution in dogs with a history of seizures or neurological disorders.
⚠ Not recommended for breeding, pregnant, or lactating dogs (safety not evaluated).
⚠ Store safely away from children and pets to prevent accidental ingestion.
Shipping Policy: We offer all types of shipping options (Ground, Express, Priority, International) depending on the urgency of the product requirements. To know about our shipping policy in detail, click here.
Refund policy: If you face any issue with our product and want to return it, read our refund policy carefully.
Simparica Trio is a once-a-month chewable tablet that protects dogs 5.6-11.0 lbs from fleas, ticks, heartworms, roundworms, and hookworms.
It starts killing fleas within 4 hours and ticks within 8 hours of administration.
Yes, it can be given with or without food, and most dogs enjoy its liver-flavored taste.
Yes! By eliminating deer ticks, Simparica Trio helps reduce the risk of Lyme disease transmission.
Administer the missed dose immediately, then resume the regular monthly schedule. If unsure, consult your veterinarian.
If you notice any omissions or errors in the product information on this page, please use the correction request form below.
Correction Request Form